Twisting tails exposed
نویسندگان
چکیده
منابع مشابه
Twisting tails exposed
The mechanism by which the ligand occupancy state of the T cell receptor complex is converted into intracellular signaling information has been a controversial topic. Although the majority of structural studies argue against a conformational change, recent studies support the possibility for such a change within the CD3 components of the TCR complex. In this commentary, the evidence for TCR con...
متن کاملTwisting tails exposed: the evidence for TCR conformational change
The mechanism by which the ligand occupancy state of the T cell receptor complex is converted into intracellular signaling information has been a controversial topic. Although the majority of structural studies argue against a conformational change, recent studies support the possibility for such a change within the CD3 components of the TCR complex. In this commentary, the evidence for TCR con...
متن کاملSolvent-exposed tails as prestalk transition states for membrane fusion at low hydration.
Membrane fusion is a key step in intracellular trafficking and viral infection. The underlying molecular mechanism is poorly understood. We have used molecular dynamics simulations in conjunction with a coarse grained model to study early metastable and transition states during the fusion of two planar palmitoyl-oleoyl-phosphatidylcholine (POPC) bilayers separated by five waters per lipid in th...
متن کاملTwisting S-branes
Smooth time dependent supergravity solutions corresponding to analytic continuations of Kerr black holes are constructed and limits with a local de Sitter phase are found. These solutions are non-singular due to a helical twist in space and a fine tuning of the energy flow in the spacetime. For the extremal limit in which the mass and twist parameters are equal the S-brane undergoes de Sitter e...
متن کاملHeads and tails: simultaneous exposed and buried interface imaging of monolayers.
We have simultaneously imaged the chemically bound head groups and exposed tail groups in bicomponent alkanethiolate self-assembled monolayers on Au{111} with molecular resolution. This has enabled us to resolve the controversy of scanning tunneling microscopy image interpretation and to measure the molecular polar tilt and azimuthal angles. Our local measurements demonstrate that ordered domai...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2005
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.20050179